A potent and selective, cell-permeable inhibitor of nitric oxide (NO)-sensitive soluble guanylyl cyclase (sGC). Inhibition is irreversible. Inhibits also the basal, the YC-1 and the coenhanced sGC activity. Complete inhibition of NO-induced relaxation in vascular and nonvascular smooth muscle at 1μM. Alternative name: 4H-8-Bromo-1,2,4-oxadiazolo(3,4-d)benz(b)(1,4)oxazin-1-one. Formula: C9H5BrN2O3. MW: 269.1. Purity: ≥98% (TLC). Solubility: Soluble in DMSO or 100% ethanol; insoluble in water. Long Term Storage: -20°C. Handling: Protect from moisture.